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Therefore, the final diagnosis was pre-fibrotic primary myelofibrosis according to the 2016 WHO classification, Dynamic International Prognostic Scoring System (DIPSS) plus 2 (intermediate-2). To our knowledge, we report uncommon case of primary myelofibrosis associated with extra-medullary myeloid proliferation of the right periadrenal tissue.To our knowledge, we report uncommon case of primary myelofibrosis associated with extra-medullary myeloid proliferation of the right periadrenal tissue. Gastric cancer in pregnancy is a very rare case with an incidence of 0.016% and is mostly detected in a locally advanced or advanced stage due to misinterpretation of non-specific signs and symptoms. Management of gastric cancer in pregnancy should emphasize mother and fetal survival. Currently, there is no diagnostic and management guidance for gastric cancer in pregnancy. The purpose of this study is to ascertain how to diagnose and manage gastric cancer in pregnancy. This study is an evidence-based case report performed in Digestive Division of Department of Surgery in Cipto Mangunkusumo hospital in September-October 2017. Literature search on databases such as Cochrane, PubMed, ScienceDirect, and Scholar Google used keywords like "gastric cancer" AND "pregnant" OR "pregnancy" with inclusion criteria which are systematic review, randomized-clinical trial (RCT), cohort study, case report, or case series, performed in human and published in the last 10 years in English language. Critical appraisal is done according to Oxford Centre For Evidence-Based Medicine 2011. This work is reported in line with the SCARE criteria. There are 9 case-report studies and 1 case-control study. Radiology examination includes endoscopy, MRI, and CT scan. Management is given according to cancer stage which is; surgery, surgery with adjuvant therapy, and palliative chemotherapy. Radiology examinations with a lower risk of adverse effects are endoscopy and MRI. CT scan may be performed when the benefits exceed the risk. Surgery and chemoradiation have the lowest rate of adverse effects when done in the second and third trimester.Radiology examinations with a lower risk of adverse effects are endoscopy and MRI. CT scan may be performed when the benefits exceed the risk. Surgery and chemoradiation have the lowest rate of adverse effects when done in the second and third trimester. Gastric pseudotumors are rare entities whose clinical presentation resembles typical gastric neoplasias, often making them unrecognized unless other causes are considered. We present a case report of a patient that debuts with dysphagia, with an abdominal computed axial tomography (CAT) scan revealing a mass at the gastro-esophageal junction suggestive of malignant origin, with studies revealing it to be Immunoglobulin G4-related (IgG4). The diagnosis and identification of IgG4-related gastric pseudotumors is very complicated, often and most commonly an incidental diagnosis upon histologic analysis, as is the situation in this case. Understanding its clinical course and early diagnosis can reduce unwarranted surgical intervention in some patients with IgG4-related disease.Understanding its clinical course and early diagnosis can reduce unwarranted surgical intervention in some patients with IgG4-related disease. Patients with osteochondromatosis have a higher risk of malignant transformation into secondary chondrosarcoma. Chondrosarcoma at the pelvic region tends to present late and therefore pose a significant challenge for orthopedic surgeons because of the large tumor size, local extension, and complex anatomy with proximity to major neurovascular structure, intestinal and urinary tract. A 44-year-old male presented the chief complaint of 15 years growing lumps on his left buttock and right groin, presenting with pain. Plain radiography revealed popcorn calcification at the left iliac wing and right superior pubic rami. Multiple exostoses were also visible. MRI showed a larger tumor diameter at the left iliac wing by 33 cm and right pubic rami by 13 cm. https://www.selleckchem.com/products/forskolin.html The histopathological result from the biopsy suggested low-grade chondrosarcoma. The patient underwent pelvic resection type I and III in two-stage surgery. About one month after the first surgery, there was a postoperative infection. Debridement and antibiotic therapy resulted in a desirable functional outcome with an MSTS score 27 and no local recurrence sign during a one-year follow-up. Low-grade chondrosarcomas are not sensitive to radiation and chemotherapy; wide surgical resection is the mainstay of treatment. Chondrosarcoma at the iliac wing can be treated by pelvic resection type I, and further reconstruction needed to prevent pelvic tilting. Chondrosarcoma at pubic rami can be treated by pelvic resection type III. Proper patient selections, preoperative planning, and wide surgical margins with reconstruction provide desirable local control and clinical outcomes following pelvic resection.Proper patient selections, preoperative planning, and wide surgical margins with reconstruction provide desirable local control and clinical outcomes following pelvic resection. Rhabdomyosarcoma (RMS) arises from mesenchymal cells committed to skeletal muscle. It is the most frequent soft-tissue sarcoma in children and makes up 5% of all pediatric malignant tumors. In this population, there are two main histological forms, which are the embryonal or the alveolar RMS. The retro auricular location is extremely rare. We present 2 cases of children with left retro-auricular RMS occurring at a very early stage of post natal development. Two children were included in the RMS 2005 Protocol. The first child, aged 5-days, was managed by surgical resection in two steps after a previous incomplete resection which was followed by 8 chemotherapy cycle. The second, aged 3-days, was managed by surgical resection of the tumor bed, completed by 8 chemotherapy cycle. On regular follow up for over 6 years after the diagnosis, both patients are free of recurrence. RMS is a fast-growing malignant and aggressive tumor originating from skeletal muscle. It occurs in the first decade of life and is associated with genetic conditions.

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